Pub. Date : 2005
PMID : 15647510
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The accumulation of MMS-induced single strand breaks in G1 phase is recombinogenic in DNA polymerase beta defective mammalian cells. | Methyl Methanesulfonate | DNA polymerase beta | Homo sapiens |
| 2 | When replicating Pol beta null cells are treated with MMS, a rapid phosphorylation of histone H2AX is detected in the nuclei of S phase cells, indicating that double strand breaks (DSB) are formed in response to unrepaired SSB. | Methyl Methanesulfonate | DNA polymerase beta | Homo sapiens |