Pub. Date : 2004 Nov
PMID : 15624308
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Delayed radioprotection by NFkappaB-mediated induction of Sod2 (MnSOD) in SA-NH tumor cells after exposure to clinically used thiol-containing drugs. | Sulfhydryl Compounds | superoxide dismutase 2 | Homo sapiens |
2 | Delayed radioprotection by NFkappaB-mediated induction of Sod2 (MnSOD) in SA-NH tumor cells after exposure to clinically used thiol-containing drugs. | Sulfhydryl Compounds | superoxide dismutase 2 | Homo sapiens |
3 | Manganese superoxide dismutase (Sod2) is one such gene whose expression levels have been shown to be elevated after exposure to the thiol compounds WR-1065 and N-acetyl-L-cysteine (NAC), resulting in an increase in radiation resistance. | Sulfhydryl Compounds | superoxide dismutase 2 | Homo sapiens |
4 | This delayed radioprotective effect correlated with elevated Sod2 protein levels in wild-type SA-NH tumor cells but was not observed in SA-NH+mIkappaBalpha1 cells, indicating that interference with thiol-induced NFKB activation abrogates this delayed radioprotective effect. | Sulfhydryl Compounds | superoxide dismutase 2 | Homo sapiens |