Title : In vitro inhibitory effect of 1-aminobenzotriazole on drug oxidations catalyzed by human cytochrome P450 enzymes: a comparison with SKF-525A and ketoconazole.

Pub. Date : 2003

PMID : 15618748






1 Functional Relationships(s)
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1 Ketoconazole inhibited all tested drug oxidations, however, its inhibitory effect on CYP1A2-dependent activities was very weak (50% inhibition at 120 microM). Ketoconazole cytochrome P450 family 1 subfamily A member 2 Homo sapiens