Title : Caspase-8 can be activated by interchain proteolysis without receptor-triggered dimerization during drug-induced apoptosis.

Pub. Date : 2005 Feb 18

PMID : 15611097






1 Functional Relationships(s)
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1 Using an in vivo affinity labeling approach, we demonstrate that caspase-8 is activated in etoposide-treated cells in vivo in the absence of the receptor-induced death-inducing signaling complex formation. Etoposide caspase 8 Homo sapiens