Title : Development and validation of a high-throughput radiometric CYP3A4/5 inhibition assay using tritiated testosterone.

Pub. Date : 2005 Mar

PMID : 15608130






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 This assay thus represents a high-throughput version of the classical testosterone 6beta-hydroxylation assay, which is the most widely used method to assess the potential for CYP3A4/5 inhibition of new chemical entities. testosterone 6beta cytochrome P450 family 3 subfamily A member 4 Homo sapiens