Title : BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase.

Pub. Date : 2005 Jan

PMID : 15601839






2 Functional Relationships(s)
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1 Here we report that the human BTB-Kelch protein Keap1, a negative regulator of the antioxidative transcription factor Nrf2, binds to CUL3 and Nrf2 via its BTB and Kelch domains, respectively. btb NFE2 like bZIP transcription factor 2 Homo sapiens
2 Here we report that the human BTB-Kelch protein Keap1, a negative regulator of the antioxidative transcription factor Nrf2, binds to CUL3 and Nrf2 via its BTB and Kelch domains, respectively. btb NFE2 like bZIP transcription factor 2 Homo sapiens