Title : Efficacy of Targretin on methylnitrosourea-induced mammary cancers: prevention and therapy dose-response curves and effects on proliferation and apoptosis.

Pub. Date : 2005 Feb

PMID : 15591091






2 Functional Relationships(s)
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1 Determination of serum IGF1 levels showed that treatment of rats with highly effective doses of Targretin at 272 mg/kg diet or at 60 or 20 mg/kg body wt/day by gavage caused significantly decreased serum IGF1 levels. Bexarotene insulin-like growth factor 1 Rattus norvegicus
2 Determination of serum IGF1 levels showed that treatment of rats with highly effective doses of Targretin at 272 mg/kg diet or at 60 or 20 mg/kg body wt/day by gavage caused significantly decreased serum IGF1 levels. Bexarotene insulin-like growth factor 1 Rattus norvegicus