Title : Reactive oxygen species blockade and action of insulin on expression of angiotensinogen gene in proximal tubular cells.

Pub. Date : 2004 Dec

PMID : 15590980






2 Functional Relationships(s)
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1 Co-incubation of IRPTCs with tiron, DPI, losartan, PD123319, perindopril, GF 109203X or azaserine prevented ROS generation, restoring the inhibitory action of insulin on ANG gene expression and on p44/42 MAPK phosphorylation. Losartan mitogen activated protein kinase 3 Rattus norvegicus
2 Co-incubation of IRPTCs with tiron, DPI, losartan, PD123319, perindopril, GF 109203X or azaserine prevented ROS generation, restoring the inhibitory action of insulin on ANG gene expression and on p44/42 MAPK phosphorylation. Losartan mitogen activated protein kinase 3 Rattus norvegicus