Title : Involvement of Mrp2 in hepatic and intestinal disposition of dinitrophenyl-S-glutathione in partially hepatectomized rats.

Pub. Date : 2005 Mar

PMID : 15590889






2 Functional Relationships(s)
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1 Involvement of Mrp2 in hepatic and intestinal disposition of dinitrophenyl-S-glutathione in partially hepatectomized rats. S-(2,4-dinitrophenyl)glutathione ATP binding cassette subfamily C member 2 Rattus norvegicus
2 The ability of the liver and small intestine for secretion of dinitrophenyl-S-glutathione (DNP-SG), a substrate for multidrug resistance-associated protein 2 (Mrp2), into bile and lumen, respectively, as well as expression of Mrp2 in both tissues, were assessed in 70-75% hepatectomized rats. S-(2,4-dinitrophenyl)glutathione ATP binding cassette subfamily C member 2 Rattus norvegicus