Title : Deacylation and palmitoylation of lipid A by Salmonellae outer membrane enzymes modulate host signaling through Toll-like receptor 4.

Pub. Date : 2004

PMID : 15588428






3 Functional Relationships(s)
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1 Deacylation and palmitoylation of lipid A by Salmonellae outer membrane enzymes modulate host signaling through Toll-like receptor 4. Lipid A toll like receptor 4 Homo sapiens
2 The acylation state of lipid A can alter host recognition and signaling by Toll-like receptor (TLR) 4, and may play an important role in host defenses against Salmonellae infection. Lipid A toll like receptor 4 Homo sapiens
3 These results suggest that PagL and PagP modify lipid A to reduce TLR4-signaling as part of Salmonellae adaptation to the host environment. Lipid A toll like receptor 4 Homo sapiens