Pub. Date : 2005 Feb 11
PMID : 15572372
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | AMP-activated protein kinase mediates phenobarbital induction of CYP2B gene expression in hepatocytes and a newly derived human hepatoma cell line. | Phenobarbital | cytochrome P450 family 2 subfamily B member 6 | Homo sapiens |
| 2 | Expression of a constitutively active form of AMPK mimics the PB induction of CYP2B6 and CYP2B1 gene expression. | Phenobarbital | cytochrome P450 family 2 subfamily B member 6 | Homo sapiens |
| 3 | Our data strongly support a role for AMPK in the PB induction of CYP2B gene expression and provide new insights into the regulation of gene expression by barbiturate drugs. | Phenobarbital | cytochrome P450 family 2 subfamily B member 6 | Homo sapiens |