Title : Glucose stimulates the expression and activities of nitric oxide synthases in incubated rat islets: an effect counteracted by GLP-1 through the cyclic AMP/PKA pathway.

Pub. Date : 2005 Feb

PMID : 15558323






1 Functional Relationships(s)
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1 The addition of glucagon-like-peptide 1 (GLP-1) or dibutyryl-cAMP to islets incubated with 20 mmol/l glucose results in a marked suppression of iNOS expression and activity, a reduction in ncNOS activity and increased insulin release. Bucladesine nitric oxide synthase 2 Rattus norvegicus