Title : Src phosphorylation of Alix/AIP1 modulates its interaction with binding partners and antagonizes its activities.

Pub. Date : 2005 Feb 4

PMID : 15557335






1 Functional Relationships(s)
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1 A proline-rich region in the C terminus of Alix bound the Src SH3 domain, but this interaction was dependent on the release of the Src SH2 domain from its Src internal ligand either by interaction with Alix Tyr319 or by mutation of Src Tyr527. Proline SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens