Title : Effects of COX-2 inhibitors on ROS produced by Chlamydia pneumoniae-primed human promonocytic cells (THP-1).

Pub. Date : 2004 Dec 24

PMID : 15555544






2 Functional Relationships(s)
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1 COX-2 inhibitors inhibited in a dose-dependent manner the luminol-enhanced CL while ibuprofen and diclofenac increased the chemiluminescence response. Ibuprofen mitochondrially encoded cytochrome c oxidase II Homo sapiens
2 By EPR spin trapping, COX-2 inhibitors, ibuprofen, and diclofenac, exhibited a dose-dependent inhibiting effect (10 and 100muM) on the EPR signal appearance. Ibuprofen mitochondrially encoded cytochrome c oxidase II Homo sapiens