Title : Cyclooxygenase-2 suppresses hypoxia-induced apoptosis via a combination of direct and indirect inhibition of p53 activity in a human prostate cancer cell line.

Pub. Date : 2005 Feb 4

PMID : 15550400






1 Functional Relationships(s)
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Compound Name
Protein Name
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1 Cyclooxygenase (COX)-2, an inducible enzyme that catalyzes the conversion of arachidonic acid to prostaglandins and other eicosanoids, is also induced by hypoxia. Eicosanoids mitochondrially encoded cytochrome c oxidase II Homo sapiens