Title : Possible pathophysiological roles of mitogen-activated protein kinases (MAPKs) in endometriosis.

Pub. Date : 2004 Nov

PMID : 15550066






2 Functional Relationships(s)
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1 Effects of PD98059, SB202190 and SP600125 (inhibitors of ERK, p38 and JNK, respectively) on IL-1beta-induced secretion of IL-6 and IL-8, and on IL-1beta-induced expression of cyclo-oxygenase-2 (COX-2) in endometriotic cells were studied. pyrazolanthrone interleukin 1 beta Homo sapiens
2 Both SB202190 and SP600125 suppressed IL-1beta-induced secretion of IL-6 and IL-8, and PD98059 suppressed IL-1beta-induced secretion of IL-8. pyrazolanthrone interleukin 1 beta Homo sapiens