Title : Infertility in 5,10-methylenetetrahydrofolate reductase (MTHFR)-deficient male mice is partially alleviated by lifetime dietary betaine supplementation.

Pub. Date : 2005 Mar

PMID : 15548731






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Infertility in 5,10-methylenetetrahydrofolate reductase (MTHFR)-deficient male mice is partially alleviated by lifetime dietary betaine supplementation. Betaine methylenetetrahydrofolate reductase Mus musculus
2 Infertility in 5,10-methylenetetrahydrofolate reductase (MTHFR)-deficient male mice is partially alleviated by lifetime dietary betaine supplementation. Betaine methylenetetrahydrofolate reductase Mus musculus
3 We postulate that the adverse effects of MTHFR deficiency on spermatogenesis, may, in part, be mediated by alterations in the transmethylation pathway and suggest that betaine supplementation may provide a means to bypass MTHFR deficiency and its adverse effects on spermatogenesis by maintaining normal methylation levels within male germ cells. Betaine methylenetetrahydrofolate reductase Mus musculus