Title : The interactions between the N-terminal and C-terminal domains of the human UDP-glucuronosyltransferases are partly isoform-specific, and may involve both monomers.

Pub. Date : 2004 Dec 15

PMID : 15548391






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The UGT1A4 was selected because it glucuronidates neither entacapone nor scopoletin at significant rates. entacapone UDP glucuronosyltransferase family 1 member A4 Homo sapiens
2 Interestingly, the ratio of entacapone to scopoletin glucuronidation rates in the co-infected cells was dependent on, and markedly increased with, the probability that 1A9Sol forms hetero-dimers with UGT1A4. entacapone UDP glucuronosyltransferase family 1 member A4 Homo sapiens