Title : A PXR reporter gene assay in a stable cell culture system: CYP3A4 and CYP2B6 induction by pesticides.

Pub. Date : 2004 Dec 15

PMID : 15548381






1 Functional Relationships(s)
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1 The abilities of organochlorine (OC), organophosphate (OP) and pyrethroid pesticides (PY) to activate hPXR were also assessed and found to be consistent with the abilities of these compounds to induce CYP3A4 and CYP2B6 in primary culture of human hepatocytes. Pyrethrins nuclear receptor subfamily 1 group I member 2 Homo sapiens