CPRiL

6 Functional Relationships(s) Download
	Sentence	Compound Name	Protein Name	Organism
1	In the HCO(3)(-)-free condition, the V(h,ACh) was also blocked by bumetanide, a blocker of Na(+)-K(+)-2Cl(-) cotransporter (NKCC).	Bicarbonates	acyl-CoA thioesterase 12	Rattus norvegicus
2	In the presence of HCO(3)(-) (24 meq, bubbled with 5% CO(2)), however, the V(h,ACh) was not blocked by bumetanide, but it was suppressed by ethylisopropylamiloride (EIPA), a Na(+)/H(+) exchanger (NHE) inhibitor.	Bicarbonates	acyl-CoA thioesterase 12	Rattus norvegicus
3	ACh induced a prominent acidification of pH(i) in the presence of HCO(3)(-), and the acidification was further increased by EIPA treatment.	Bicarbonates	acyl-CoA thioesterase 12	Rattus norvegicus
4	Without HCO(3)(-), an application of ACh strongly accelerated the NKCC activity that was measured from the decay of pH(i) during the application of NH(4)(+) (20 mM).	Bicarbonates	acyl-CoA thioesterase 12	Rattus norvegicus
5	Notably, the ACh-induced activation of NKCC was largely suppressed in the presence of HCO(3)(-).	Bicarbonates	acyl-CoA thioesterase 12	Rattus norvegicus
6	The regulation of NKCC and NHE by ACh is strongly affected by the physiological level of HCO(3)(-).	Bicarbonates	acyl-CoA thioesterase 12	Rattus norvegicus