Title : Fluctuations of intracellular iron modulate elastin production.

Pub. Date : 2005 Jan 21

PMID : 15537639






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1 Our experimental evidence also demonstrates the existence of an opposite effect, in which higher, but not cytotoxic concentrations of iron (100-400 microm) induced the production of intracellular reactive oxygen species that coincided with a significant decrease in elastin message stability and the disappearance of iron-dependent stimulatory effect on elastogenesis. Reactive Oxygen Species elastin Homo sapiens