Title : AT2 receptor and apoptosis during AT1 receptor blockade in reperfused myocardial infarction in the rat.

Pub. Date : 2004 Jul

PMID : 15532725






1 Functional Relationships(s)
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1 Compared to controls, candesartan significantly (p < 0.001) limited increases in left atrial pressure, improved positive LV dP/dtmax and negative dP/dtmin, normalized LV ejection fraction, improved LV diastolic function, limited infarct expansion, decreased infarct size and apoptosis, and increased AT2R protein (not AT1R) in the reperfused ischemic zone. candesartan angiotensin II receptor, type 2 Rattus norvegicus