Title : Ethanol blocks leukocyte recruitment and endothelial cell activation in vivo and in vitro.

Pub. Date : 2004 Nov 15

PMID : 15528377






1 Functional Relationships(s)
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1 Ethanol, at concentrations within the range found in human blood after acute exposure and below the levels that induce cytotoxicity (0.1-0.5%), did not induce endothelial cell activation, but significantly inhibited TNF-mediated endothelial cell activation, as measured by adhesion molecule (E-selectin, ICAM-1, VCAM-1) expression and chemokine (IL-8, MCP-1, RANTES) production and leukocyte adhesion in vitro. Ethanol C-C motif chemokine ligand 2 Homo sapiens