Title : Multiple transport systems mediate the hepatic uptake and biliary excretion of the metabolically stable opioid peptide [D-penicillamine2,5]enkephalin.

Pub. Date : 2005 Feb

PMID : 15528320






1 Functional Relationships(s)
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1 3H-DPDPE uptake in suspended Wistar rat hepatocytes was primarily (>95%) due to temperature-dependent transport mechanisms; similar results were obtained in suspended hepatocytes from Mrp2-deficient (TR-) rats. Tritium ATP binding cassette subfamily C member 2 Rattus norvegicus