Pub. Date : 2004 Nov 15
PMID : 15522889
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Two chemical inhibitors of glycogen synthase kinase (GSK)-3beta, indirubin-3-monoxime and kenpaullone, were found to increase neuronal differentiation in ventral mesencephalon precursor cultures. | kenpaullone | glycogen synthase kinase 3 alpha | Homo sapiens |
| 2 | In addition, the GSK-3beta-specific inhibitor kenpaullone increased the size of the DA neuron population through conversion of precursors expressing the orphan nuclear receptor-related factor 1 into tyrosine hydroxylase positive neurons, thereby mimicking an effect of Wnts. | kenpaullone | glycogen synthase kinase 3 alpha | Homo sapiens |