Title : The metabolism of beta-amyloid converting enzyme and beta-amyloid precursor protein processing.

Pub. Date : 2004 Dec 3

PMID : 15522224






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Mutagenesis of the identified cleavage sites revealed that the mutants D379A, D379L or D379E block the degradation of BACE into the approximately 12kDa product, confirming the importance of Asp(379). Aspartic Acid beta-secretase 1 Homo sapiens