Pub. Date : 2004 Nov 26
PMID : 15518636
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Central Ang II administration to vehicle-treated SHRs further increased blood pressure, provoked drinking, increased tyrosine hydroxylase (TH) mRNA expression in the locus coeruleus, and stimulated sympathoadrenal catecholamine release. | Catecholamines | angiotensinogen | Rattus norvegicus |
2 | Pretreatment with the AT(1) receptor antagonist eliminated Ang II-induced increases in blood pressure, water intake, and sympathoadrenal catecholamine release; inhibited peripheral and brain AT(1) receptors; increased AT(2) receptor binding in the locus coeruleus, inferior olive, and adrenal cortex; and decreased AT(2) receptor binding in the adrenal medulla. | Catecholamines | angiotensinogen | Rattus norvegicus |