Title : Epidermal peroxisome proliferator-activated receptor gamma as a target for ultraviolet B radiation.

Pub. Date : 2005 Jan 7

PMID : 15516334






2 Functional Relationships(s)
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1 The treatment of epidermal cells with the PPAR gamma-specific agonist ciglitazone or azPC augmented cyclooxygenase-2 expression and enzyme activity induced by phorbol 12-myristate-13-acetate or interleukin-1 beta. Tetradecanoylphorbol Acetate prostaglandin-endoperoxide synthase 2 Homo sapiens
2 Lipid extracts from the cell homogenate of UVB-irradiated, but not control, cells contained a PPAR gamma-agonistic activity identified by reporter assay, and this activity up-regulated cyclooxygenase-2 expression induced by phorbol 12-myristate-13-acetate. Tetradecanoylphorbol Acetate prostaglandin-endoperoxide synthase 2 Homo sapiens