Title : Cutaneous T-cell lymphoma: malignant proliferation of T-regulatory cells.

Pub. Date : 2005 Feb 15

PMID : 15514008






2 Functional Relationships(s)
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1 We now report that the T-cell receptor (TCR) of the CD4(+) CTCL cells is triggered after interaction with DCs loaded with apoptotic CTCL cells, as shown by reduced membrane expression of CD3 and the TCR, up-regulation of cytotoxic T lymphocyte antigen-4 (CTLA-4), and calcium mobilization. Calcium TSPY like 2 Homo sapiens
2 We now report that the T-cell receptor (TCR) of the CD4(+) CTCL cells is triggered after interaction with DCs loaded with apoptotic CTCL cells, as shown by reduced membrane expression of CD3 and the TCR, up-regulation of cytotoxic T lymphocyte antigen-4 (CTLA-4), and calcium mobilization. Calcium TSPY like 2 Homo sapiens