Title : A cyclopent-2-enecarbonyl group mimics proline at the P2 position of prolyl oligopeptidase inhibitors.

Pub. Date : 2004 Nov 4

PMID : 15509157






3 Functional Relationships(s)
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1 A cyclopent-2-enecarbonyl group mimics proline at the P2 position of prolyl oligopeptidase inhibitors. Proline prolyl endopeptidase Homo sapiens
2 With the aim to replace the natural amino acid proline by a proline mimetic structure, a cyclopent-2-enecarbonyl moiety was studied at the P2 position of prolyl oligopeptidase (POP) inhibitors. Proline prolyl endopeptidase Homo sapiens
3 The cyclopent-2-enecarbonyl moiety proved to be an excellent proline mimetic at the P2 position of POP inhibitors. Proline prolyl endopeptidase Homo sapiens