Title : Ibuprofen and Alzheimer's disease.

Pub. Date : 2004

PMID : 15506544






1 Functional Relationships(s)
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Protein Name
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1 Ibuprofen, a commonly used over-the-counter nonsteroidal anti-inflammatory drug (NSAID) that is a cyclooxygenase (COX)-1 and COX-2 inhibitor as well as a peroxisome proliferator-activated receptor (PPAR) agonist, decreases the production of nitric oxide (NO), protects neurons against glutamate toxicity and decreases the production of proinflammatory cytokines. Ibuprofen mitochondrially encoded cytochrome c oxidase II Homo sapiens