Title : Implication of prostaglandin E(2) in TNF-alpha-induced release of m-calpain from HCS-2/8 chondrocytes. Inhibition of m-calpain release by NSAIDs.

Pub. Date : 2004 Nov

PMID : 15501405






1 Functional Relationships(s)
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1 NSAIDs examined (aspirin, loxoprofen-SRS, diclofenac sodium, indomethacin and NS398) inhibited m-calpain release and production of prostaglandin E(2) (PGE(2)) induced by 10 ng/ml TNF-alpha. N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide tumor necrosis factor Homo sapiens