Title : Nitric oxide decreases IGF-1 receptor function in vitro; glutathione depletion enhances this effect in vivo.

Pub. Date : 2004 Nov

PMID : 15501401






1 Functional Relationships(s)
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1 Increasing either dithiothreitol or reduced glutathione (GSH) content of the phosphorylation buffer to protect thiol groups blocks NO inhibition of IGF-RK substrate phosphorylation. Dithiothreitol insulin like growth factor 1 Homo sapiens