Pub. Date : 2004 Jun
PMID : 15499183
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | More recently, it has been reported that megalin, a giant endocytic receptor abundantly expressed at the apical membrane of renal proximal tubules, plays an important role in binding and endocytosis of aminoglycosides in the proximal tubular cells. | Aminoglycosides | LDL receptor related protein 2 | Homo sapiens |
| 2 | In this review, we summarize recent advances in the understandings of the molecular mechanisms responsible for renal accumulation of aminoglycosides, especially megalin-mediated endocytosis. | Aminoglycosides | LDL receptor related protein 2 | Homo sapiens |