Title : Thermodynamics of mRNA 5' cap binding by eukaryotic translation initiation factor eIF4E.

Pub. Date : 2004 Oct 26

PMID : 15491137






1 Functional Relationships(s)
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1 A nontrivial, statistically important isothermal enthalpy-entropy compensation has been detected (T(c) = 399 +/- 24 K), which points to significant fluctuations of apo-eIF4E and indicates that the cap-binding microstate lies 9.66 +/- 1.7 kJ mol(-1) below the mean energy of all available conformational states. cap eukaryotic translation initiation factor 4E Homo sapiens