Title : Central role of the threonine residue within the p+1 loop of receptor tyrosine kinase in STAT3 constitutive phosphorylation in metastatic cancer cells.

Pub. Date : 2004 Nov

PMID : 15485908






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The receptor tyrosine kinases (RTKs) RET, MET, and RON all carry the Met(p+1loop)-->Thr point mutation (i.e., 2B mutation), leading to the formation of tumors with high metastatic potential. Threonine ret proto-oncogene Homo sapiens