Pub. Date : 2004 Oct
PMID : 15483417
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We here describe the effects of N-acetylcysteine, deferoxamine, or both in the treatment of CCl4-induced hepatic failure. | Deferoxamine | C-C motif chemokine ligand 4 | Rattus norvegicus |
| 2 | MEASUREMENTS AND MAIN RESULTS: N-acetylcysteine plus deferoxamine treatment significantly attenuated hepatic and central nervous system oxidative damage after acute hepatic failure induced by CCl4. | Deferoxamine | C-C motif chemokine ligand 4 | Rattus norvegicus |
| 3 | CONCLUSIONS: Our data provide the first experimental demonstration that N-acetylcysteine plus deferoxamine reduces mortality rate, decreases oxidative stress, and limits inflammatory infiltration and hepatocyte necrosis induced by CCl4 in the rat. | Deferoxamine | C-C motif chemokine ligand 4 | Rattus norvegicus |