Title : Excessive expression of acetylcholinesterase impairs glutamatergic synaptogenesis in hippocampal neurons.

Pub. Date : 2004 Oct 13

PMID : 15483114






2 Functional Relationships(s)
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1 The noncatalytic functions of AChE have been attributed to its peripheral anionic site (PAS)-mediated protein-protein interactions. Aminosalicylic Acid acetylcholinesterase (Cartwright blood group) Homo sapiens
2 Moreover, the PAS blockade-induced glutamatergic impairments were associated with a depressed expression of beta-neurexins and an accumulation of other synaptic proteins, including neuroligins, and were mostly preventable by antisense suppression of AChE expression. Aminosalicylic Acid acetylcholinesterase (Cartwright blood group) Homo sapiens