Title : GSK-3beta inhibition by lithium confers resistance to chemotherapy-induced apoptosis through the repression of CD95 (Fas/APO-1) expression.

Pub. Date : 2004 Nov 1

PMID : 15475000






1 Functional Relationships(s)
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1 Moreover, the overexpression of an inactivated GSK-3beta mutant counteracted the stimulatory effects of etoposide and camptothecin on a luciferase reporter plasmid driven by a p53-responsive sequence from the CD95 gene. Camptothecin tumor protein p53 Homo sapiens