Pub. Date : 2004 Nov 15
PMID : 15470720
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Because one of the main downstream effectors of the cAMP signaling pathway is cAMP-response element binding (CREB), we reasoned that it might affect the expression of genes associated with differentiation and apoptotic events in NBP2 cells. | Cyclic AMP | cAMP responsive element binding protein 1 | Mus musculus |
| 2 | Because one of the main downstream effectors of the cAMP signaling pathway is cAMP-response element binding (CREB), we reasoned that it might affect the expression of genes associated with differentiation and apoptotic events in NBP2 cells. | Cyclic AMP | cAMP responsive element binding protein 1 | Mus musculus |
| 3 | Our data suggest that increased levels of cAMP function through not only CREB but also other signaling pathways that account for the additional cAMP-induced effects, including irreversible differentiation and onset of apoptosis during partial inhibition of proteasome in NBP2 cells. | Cyclic AMP | cAMP responsive element binding protein 1 | Mus musculus |