Title : Vasoactive intestinal peptide induces neuroendocrine differentiation in the LNCaP prostate cancer cell line through PKA, ERK, and PI3K.

Pub. Date : 2005 Apr 1

PMID : 15468165






1 Functional Relationships(s)
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1 mitogen-activated protein kinase kinase (MEK) and phosphoinositide 3-kinase (PI3K) appear to be also involved since the inhibitors PD98059 and wortmannin abolished ERK1/2 phosphorylation and decreased NE differentiation induced by VIP. Wortmannin mitogen-activated protein kinase 3 Homo sapiens