Title : Treatment of chronic myeloid leukemia cells with imatinib (STI571) impairs p53 accumulation in response to DNA damage.

Pub. Date : 2004 Sep

PMID : 15467443






4 Functional Relationships(s)
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1 Treatment of chronic myeloid leukemia cells with imatinib (STI571) impairs p53 accumulation in response to DNA damage. Imatinib Mesylate tumor protein p53 Homo sapiens
2 Treatment of chronic myeloid leukemia cells with imatinib (STI571) impairs p53 accumulation in response to DNA damage. Imatinib Mesylate tumor protein p53 Homo sapiens
3 Here, we investigated the effect of STI571 treatment of CML cells on p53 regulation. Imatinib Mesylate tumor protein p53 Homo sapiens
4 CML cells expressing wild-type p53 are more resistant to treatment with STI571, but moderately more sensitive to DNA damage, than CML cells lacking p53. Imatinib Mesylate tumor protein p53 Homo sapiens