Title : Trolox selectively enhances arsenic-mediated oxidative stress and apoptosis in APL and other malignant cell lines.

Pub. Date : 2005 Feb 1

PMID : 15466933






2 Functional Relationships(s)
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1 Treatment with As(2)O(3) and trolox increased intracellular oxidative stress, as evidenced by heme oxygenase-1 (HO-1) protein levels, c-Jun terminal kinase (JNK) activation, and protein and lipid oxidation. Arsenic Trioxide mitogen-activated protein kinase 8 Homo sapiens
2 Treatment with As(2)O(3) and trolox increased intracellular oxidative stress, as evidenced by heme oxygenase-1 (HO-1) protein levels, c-Jun terminal kinase (JNK) activation, and protein and lipid oxidation. Arsenic Trioxide mitogen-activated protein kinase 8 Homo sapiens