Title : Fever of recombinant human interferon-alpha is mediated by opioid domain interaction with opioid receptor inducing prostaglandin E2.

Pub. Date : 2004 Nov

PMID : 15465601






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 It showed that IFNalpha and 129Ser-IFNalpha decreased cAMP production, induced the fever, and stimulated PGE2 to release from the hypothalamus slices, which could be blocked by naloxone, but 38Leu-IFNalpha failed. Cyclic AMP interferon alpha 1 Homo sapiens
2 It showed that IFNalpha and 129Ser-IFNalpha decreased cAMP production, induced the fever, and stimulated PGE2 to release from the hypothalamus slices, which could be blocked by naloxone, but 38Leu-IFNalpha failed. Cyclic AMP interferon alpha 1 Homo sapiens
3 It showed that IFNalpha and 129Ser-IFNalpha decreased cAMP production, induced the fever, and stimulated PGE2 to release from the hypothalamus slices, which could be blocked by naloxone, but 38Leu-IFNalpha failed. Cyclic AMP interferon alpha 1 Homo sapiens