Title : Reduction of expression of the multidrug resistance protein (MRP)1 in glioma cells by antisense phosphorothioate oligonucleotides.

Pub. Date : 2004 Aug

PMID : 15460906






1 Functional Relationships(s)
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1 20-mer phosphorothioate oligodeoxynucleotide (0.3 microM), complementary to the coding region in the MRP cDNA sequence, could significantly inhibit the growth of multidrug resistant cell lines, T98G-VP and Gli36-VP, cultured in etoposide containing medium. Etoposide ATP binding cassette subfamily C member 1 Homo sapiens