Pub. Date : 2004 Oct
PMID : 15458439
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We tested the hypothesis that the serum uric acid concentration predicts the renal vascular response to Ang II. | Uric Acid | angiotensinogen | Homo sapiens |
| 2 | Multivariable regression analysis determined if the serum uric acid concentration independently predicts the RPF response to Ang II. | Uric Acid | angiotensinogen | Homo sapiens |
| 3 | RESULTS: Uric acid concentration negatively correlated with the RPF response to Ang II (r=-0.37, P < 0.001). | Uric Acid | angiotensinogen | Homo sapiens |
| 4 | In multivariable analysis, serum uric acid concentration independently predicted the RPF response to Ang II (beta=-5.3, P < 0.001). | Uric Acid | angiotensinogen | Homo sapiens |
| 5 | CONCLUSION: Serum uric acid independently predicted blunted renal vascular responsiveness to Ang II, consistent with results from experimental hyperuricemia showing an activated intrarenal RAS. | Uric Acid | angiotensinogen | Homo sapiens |