Title : The effect of escitalopram, desipramine, electroconvulsive seizures and lithium on brain-derived neurotrophic factor mRNA and protein expression in the rat brain and the correlation to 5-HT and 5-HIAA levels.

Pub. Date : 2004 Oct 22

PMID : 15451381






2 Functional Relationships(s)
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1 In the present study we performed parallel measurements of BDNF mRNA and protein expression in the frontal cortex and hippocampus of the rat after chronic treatment with electroconvulsive seizures (ECS), lithium, desipramine or escitalopram. Desipramine brain-derived neurotrophic factor Rattus norvegicus
2 Desipramine moderately increased BDNF mRNA expression in the dentate gyrus but did not change BDNF protein in neither region. Desipramine brain-derived neurotrophic factor Rattus norvegicus