Title : Genetic alteration of catecholamine specificity in transgenic mice.

Pub. Date : 1992 Mar 1

PMID : 1542654






8 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Epinephrine-producing cells are characterized by the presence of phenylethanolamine N-methyltransferase (PNMT), which catalyzes the formation of epinephrine from norepinephrine. Epinephrine phenylethanolamine-N-methyltransferase Mus musculus
2 Epinephrine-producing cells are characterized by the presence of phenylethanolamine N-methyltransferase (PNMT), which catalyzes the formation of epinephrine from norepinephrine. Epinephrine phenylethanolamine-N-methyltransferase Mus musculus
3 Epinephrine-producing cells are characterized by the presence of phenylethanolamine N-methyltransferase (PNMT), which catalyzes the formation of epinephrine from norepinephrine. Epinephrine phenylethanolamine-N-methyltransferase Mus musculus
4 Epinephrine-producing cells are characterized by the presence of phenylethanolamine N-methyltransferase (PNMT), which catalyzes the formation of epinephrine from norepinephrine. Epinephrine phenylethanolamine-N-methyltransferase Mus musculus
5 These results indicate that the additional PNMT expression in norepinephrine-producing cells can convert these cells to the epinephrine phenotype, and suggest that norepinephrine-producing cells normally possess the basic machinery required for the synthesis of epinephrine except for PNMT. Epinephrine phenylethanolamine-N-methyltransferase Mus musculus
6 These results indicate that the additional PNMT expression in norepinephrine-producing cells can convert these cells to the epinephrine phenotype, and suggest that norepinephrine-producing cells normally possess the basic machinery required for the synthesis of epinephrine except for PNMT. Epinephrine phenylethanolamine-N-methyltransferase Mus musculus
7 These results indicate that the additional PNMT expression in norepinephrine-producing cells can convert these cells to the epinephrine phenotype, and suggest that norepinephrine-producing cells normally possess the basic machinery required for the synthesis of epinephrine except for PNMT. Epinephrine phenylethanolamine-N-methyltransferase Mus musculus
8 Thus it appears that the only major difference between norepinephrine- and epinephrine-producing cells is the expression of PNMT. Epinephrine phenylethanolamine-N-methyltransferase Mus musculus