Pub. Date : 1992
PMID : 1542151
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In this study, the influence of changing salt status and angiotensin II activity has been investigated by evaluating the QRS prolonging effects of the sodium channel blocking drug, desmethylimipramine. | Desipramine | angiotensinogen | Rattus norvegicus |
| 2 | The QRS response to desmethylimipramine and salt-loaded rats on normal salt diets receiving captopril returned to the control pattern after a subpressor infusion of angiotensin II (3 ng/min), while a higher rate of angiotensin II (10 ng/min) further enhanced the QRS prolonging effect of desmethylimipramine. | Desipramine | angiotensinogen | Rattus norvegicus |
| 3 | These data demonstrate that endogenous angiotensin II contributes to the regulation of the cardiac electro-physiological response to DMI. | Desipramine | angiotensinogen | Rattus norvegicus |