Pub. Date : 1992 Feb 14
PMID : 1540181
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | ECEs derived from these epithelial cells were very similar to the endothelial ECE in the following biochemical properties: 1) The optimum pH was 7.0; 2) the Km value for big ET-1 was approximately 30 microM; 3) the enzyme was potently inhibited by EDTA, o-phenanthroline and phosphoramidon; and 4) the enzyme did not convert big ET-2 or big ET-3. | phosphoramidon | endothelin converting enzyme 1 | Homo sapiens |
| 2 | These data suggest that phosphoramidon-sensitive ECE is involved in the processing of big ET-1 to ET-1 in the renal tubule. | phosphoramidon | endothelin converting enzyme 1 | Homo sapiens |